Problems may arise when organizational culture is not considered in the development of information systems, such as difficulties in system implementation, since users do not accept changes in their work cultures. However, current methodology designs do not contemplate cultural factors. The objective of this investigation was to identify the main cultural features shared by the users of information systems in an Argentinean university. As result of this work it was possible to identify the memes shared by the members of the community selected, and to categorize such memes according to their incidence grade. This work seeks to be an initial step towards the construction of systems that evolve along with the organizational culture they are an integral part of.